Assembly of Protein–Polysaccharide Complexes for Delivery of Bioactive Ingredients: A Perspective Paper,Journal of Agricultural and Food Chemistry

当前位置： X-MOL 学术 › J. Agric. Food Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Assembly of Protein–Polysaccharide Complexes for Delivery of Bioactive Ingredients: A Perspective Paper
Journal of Agricultural and Food Chemistry ( IF 5.7 ) Pub Date : 2019-01-14 00:00:00 , DOI: 10.1021/acs.jafc.8b06063
Zihao Wei ₁ , Qingrong Huang ₁

Affiliation

Protein–polysaccharide complexes can be created in various ways (physical mixing, enzymatic cross-linking, chemical cross-linking, and Maillard reaction), and diverse protein–polysaccharide complexes are generally grouped into non-covalent and covalent complexes. Delivery systems constructed through assembly of protein–polysaccharide complexes (DSAPC) consist of emulsion-based delivery systems, capsule-based delivery systems, molecular complexes, nanogels, core–shell particles, composite nanoparticles, and micelles. DSAPC are effective delivery vehicles in enhancing the overall efficacy of bioactive ingredients, and DSAPC may possess multiple advantages over other delivery vehicles in bioactive ingredient delivery. However, designing and applying DSAPC are still faced with some challenges, such as low loading of bioactive ingredients. Efforts are required to reconsider and improve efficiency of DSAPC in many aspects, such as controlled release and targeted delivery. On the basis of more comprehensive and deeper understandings, DSAPC can be designed more rationally for delivery of bioactive ingredients.

中文翻译：

蛋白质-多糖复合物组装的生物活性成分的传递：远景论文

可以通过多种方式（物理混合，酶促交联，化学交联和美拉德反应）创建蛋白质-多糖复合物，并且通常将各种蛋白质-多糖复合物分为非共价和共价复合物。通过组装蛋白质-多糖复合物（DSAPC）构建的传递系统包括基于乳液的传递系统，基于胶囊的传递系统，分子复合物，纳米凝胶，核-壳颗粒，复合纳米颗粒和胶束。DSAPC是增强生物活性成分整体功效的有效传递工具，而DSAPC在生物活性成分传递方面可能比其他传递媒介具有多重优势。但是，设计和应用DSAPC仍然面临一些挑战，例如生物活性成分的低负荷。需要在许多方面重新考虑DSAPC并提高DSAPC的效率，例如控释和靶向递送。在更全面，更深入的了解的基础上，可以更合理地设计DSAPC，以提供生物活性成分。

更新日期：2019-01-14

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南