A New Generation of NIR‐II Probes: Lanthanide‐Based Nanocrystals for Bioimaging and Biosensing,Advanced Optical Materials

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A New Generation of NIR‐II Probes: Lanthanide‐Based Nanocrystals for Bioimaging and Biosensing
Advanced Optical Materials ( IF 8.0 ) Pub Date : 2019-01-15 , DOI: 10.1002/adom.201801417
Yong Fan ₁ , Fan Zhang ₁

Affiliation

Fluorescence‐based imaging in the second near infrared window (NIR‐II, 1000–1700 nm) is extensively used in both fundamental scientific research and clinical practice, owing to its advances of high sensitivity and high spatiotemporal resolution with increasing tissue penetration depths. Among several NIR‐II fluorophores, recent accomplishments in biocompatible lanthanide‐based luminescent nanomaterials have aroused great interest of researchers. This progress report summarizes recent progress in controlled synthesis of lanthanide‐based NIR‐II nanomaterials and their state‐of‐the‐art in NIR‐II biomedical imaging and biosensing applications. In addition, challenges and opportunities for this kind of novel NIR‐II nanoprobes are also discussed.

中文翻译：

新一代NIR-II探针：用于生物成像和生物传感的基于镧系元素的纳米晶体

第二近红外窗口（NIR-II，1000-1700 nm）中的基于荧光的成像由于其高灵敏度和高时空分辨率随着组织穿透深度的增加而被广泛用于基础科学研究和临床实践。在几种NIR-II荧光团中，基于生物相容性镧系元素的发光纳米材料的最新成就引起了研究人员的极大兴趣。该进展报告总结了基于镧系元素的NIR-II纳米材料的可控合成及其在NIR-II生物医学成像和生物传感应用中的最新技术的最新进展。此外，还讨论了这类新型NIR-II纳米探针的挑战和机遇。

更新日期：2019-01-15

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