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STIM1 moonlights as an anchor for STING.
Nature Immunology ( IF 27.7 ) Pub Date : 2019-02-01 , DOI: 10.1038/s41590-018-0300-2 Jianjun Wu 1 , Nan Yan 1, 2
Nature Immunology ( IF 27.7 ) Pub Date : 2019-02-01 , DOI: 10.1038/s41590-018-0300-2 Jianjun Wu 1 , Nan Yan 1, 2
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STIM1 moonlights as an anchor for STING
中文翻译：
STIM1月光作为STING的锚点。
STIM1月光作为STING的锚点
更新日期：2019-01-25
STIM1 moonlights as an anchor for STING, Published online: 14 January 2019; doi:10.1038/s41590-018-0300-2
Activation of STING requires its translocation from the endoplasmic reticulum (ER) through the Golgi to vesicles, but the mechanisms that control its localization have been unclear. The ER calcium sensor STIM1 acts as an ER-retention factor that anchors STING on the ER and limits STING signaling.中文翻译：
STIM1月光作为STING的锚点。
STIM1月光作为STING的锚点
STIM1月光作为STING的锚点，在线发布：2019年1月14日; doi：10.1038 / s41590-018-0300-2
STING的激活需要其通过高尔基体从内质网（ER）转运到囊泡，但控制其定位的机制尚不清楚。ER钙传感器STIM1充当ER保留因子，可将STING固定在ER上并限制STING信号传导。
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