Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women.,Journal of Exposure Science and Environmental Epidemiology

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Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women.
Journal of Exposure Science and Environmental Epidemiology ( IF 4.1 ) Pub Date : 2019-01-08 , DOI: 10.1038/s41370-018-0109-y
Katherine E Boronow ₁ , Julia Green Brody ₁ , Laurel A Schaider ₁ , Graham F Peaslee ₂ , Laurie Havas ₃ , Barbara A Cohn ₄

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Per- and polyfluoroalkyl substances (PFASs) are used in a wide range of consumer products for their water- and grease-resistant properties, but few studies have explored this exposure route. We used multiple regression to investigate associations between six self-reported behaviors hypothesized to influence PFAS exposure and serum concentrations of six PFAS chemicals in 178 middle-aged women enrolled in the Child Health and Development Studies, about half of whom are African American. Blood samples were collected in 2010-2013, and participants were interviewed about behavior in 2015-2016. Results showed that African American women had lower levels of perfluorooctanoic acid (PFOA) and perfluorohexanesulfonic acid (PFHxS) compared with non-Hispanic white women. In African Americans, but not others, frequent consumption of prepared food in coated cardboard containers was associated with higher levels of four PFASs. Flossing with Oral-B Glide, having stain-resistant carpet or furniture, and living in a city served by a PFAS-contaminated water supply were also associated with higher levels of some PFASs. Product testing using particle-induced γ-ray emission (PIGE) spectroscopy confirmed that Oral-B Glide and competitor flosses contained detectable fluorine. Despite the delay between blood collection and interview, these results strengthen the evidence for exposure to PFASs from food packaging and implicate exposure from polytetrafluoroethylene (PTFE)-based dental floss for the first time.

中文翻译：

非裔美国人和非西班牙裔白人女性的 PFAS 血清浓度和暴露相关行为。

全氟烷基物质和多氟烷基物质 (PFAS) 因其防水和防油脂特性而被广泛用于各种消费品中，但很少有研究探索这种暴露途径。我们使用多元回归来调查 178 名参加儿童健康与发展研究的中年妇女（其中约一半是非洲裔美国人）中假设影响 PFAS 暴露的六种自我报告行为与六种 PFAS 化学物质血清浓度之间的关联。2010-2013 年采集血样，并就 2015-2016 年的行为对参与者进行了采访。结果表明，与非西班牙裔白人女性相比，非裔美国女性的全氟辛酸 (PFOA) 和全氟己烷磺酸 (PFHxS) 水平较低。在非裔美国人中，但在其他人中，经常食用涂有涂层的纸板容器中的预制食品与四种 PFAS 含量较高有关。使用 Oral-B Glide 使用牙线、使用防污地毯或家具以及生活在被 PFAS 污染的供水系统的城市也与某些 PFAS 含量较高有关。使用粒子诱导 γ 射线发射 (PIGE) 光谱的产品测试证实，Oral-B Glide 和竞争对手的牙线含有可检测到的氟。尽管采血和访谈之间存在延迟，但这些结果加强了食品包装中暴露于 PFAS 的证据，并首次暗示暴露于基于聚四氟乙烯 (PTFE) 的牙线。居住在供水受到 PFAS 污染的城市也与某些 PFAS 含量较高有关。使用粒子诱导 γ 射线发射 (PIGE) 光谱的产品测试证实，Oral-B Glide 和竞争对手的牙线含有可检测到的氟。尽管采血和访谈之间存在延迟，但这些结果加强了食品包装中暴露于 PFAS 的证据，并首次暗示暴露于基于聚四氟乙烯 (PTFE) 的牙线。居住在供水受到 PFAS 污染的城市也与某些 PFAS 含量较高有关。使用粒子诱导 γ 射线发射 (PIGE) 光谱的产品测试证实，Oral-B Glide 和竞争对手的牙线含有可检测到的氟。尽管采血和访谈之间存在延迟，但这些结果加强了食品包装中暴露于 PFAS 的证据，并首次暗示暴露于基于聚四氟乙烯 (PTFE) 的牙线。

更新日期：2019-05-16

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