Formation of Poorly Crystalline and Amorphous Precipitate, a Component of Infectious Urinary Stones: Role of Tetrasodium Pyrophosphate,Crystal Growth & Design

当前位置： X-MOL 学术 › Cryst. Growth Des. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Formation of Poorly Crystalline and Amorphous Precipitate, a Component of Infectious Urinary Stones: Role of Tetrasodium Pyrophosphate
Crystal Growth & Design ( IF 3.2 ) Pub Date : 2019-01-04 00:00:00 , DOI: 10.1021/acs.cgd.8b01581
Jolanta Prywer ₁ , Ewa Mielniczek-Brzóska ₂

Affiliation

The present study concerns an important topic regarding the search for new, improved, and effective methods of preventing the development of infectious urinary stones. In this article, the effect of tetrasodium pyrophosphate (TSPP) on the formation of a poorly crystalline and amorphous precipitate in artificial urine in the context of infectious urinary stone formation is studied. The spectrophotometric results suggest that TSPP presence shifts the formation of the poorly crystalline and amorphous precipitate (PCaAP) toward lower pH, which means that PCaAP is formed earlier. In other words, TSPP promotes the formation of PCaAP. Additionally, TSPP causes the formation of calcium pyrophosphate. These results are confirmed by X-ray diffraction and energy dispersive X-ray studies. The experimental results obtained are explained on the basis of theoretical chemical speciation analysis of chemical complexes formed in artificial urine.

中文翻译：

结晶性差和无定形沉淀物（传染性尿结石的组成部分）的形成：焦磷酸四钠的作用

本研究涉及有关寻找新的，改进的和有效的方法来预防感染性尿路结石发展的重要课题。在本文中，研究了在感染性尿结石形成的背景下焦磷酸四钠（TSPP）对人造尿液中结晶性和非晶态沉淀物形成的影响。分光光度法的结果表明，TSPP的存在将低结晶度和无定形沉淀物（PCaAP）的形成移向了较低的pH值，这意味着PCaAP的形成较早。换句话说，TSPP促进了PCaAP的形成。另外，TSPP引起焦磷酸钙的形成。这些结果通过X射线衍射和能量色散X射线研究得到了证实。

更新日期：2019-01-04

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南