当前位置:
X-MOL 学术
›
Tetrahedron Lett.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
RuO4 catalyzed dihydroxylation for the synthesis of mixed medium-chain triacylglycerols
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2015-05-05 06:17:51
K. Nandini , P. Srinivas , B.K. Bettadaiah
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2015-05-05 06:17:51
K. Nandini , P. Srinivas , B.K. Bettadaiah
![]() |
RuO4 catalyzed dihydroxylation of allyl acylates (C5 to C12) to glyceryl acylates is reported. The dihydroxylation was a major product (61–85%) with C5–C7 whereas carbonyl compounds by double bond fission were major with C8–C12 systems. 1-Hexanoylglycerol, obtained in high yields (85%), was further acylated with medium chain fatty acid chlorides to prepare mixed medium chain triglycerides (85–90%). Hence, a facile preparation of triacylglycerols such as C6–C6–C6, C6–C8–C8, C6–C10–C10, and C6–C12–C12 is accomplished.
中文翻译:
RuO4催化二羟基化反应合成中链三酰基甘油
据报道RuO 4催化烯丙基酰化物(C 5至C 12)二羟基化为甘油酰酯。二羟基化是C 5 -C 7的主要产物(61-85%),而双键裂变的羰基化合物在C 8 -C 12体系中是主要产物。以高产率(85%)获得的1-己酰甘油被中链脂肪酸氯化物进一步酰化,以制备混合中链甘油三酸酯(85-90%)。因此,可以轻松制备三酰基甘油,例如C 6 -C 6 -C 6,C 6 -C 8 -C 8,C 6 -C完成10 –C 10和C 6 –C 12 –C 12。
更新日期:2015-05-05
中文翻译:

RuO4催化二羟基化反应合成中链三酰基甘油
据报道RuO 4催化烯丙基酰化物(C 5至C 12)二羟基化为甘油酰酯。二羟基化是C 5 -C 7的主要产物(61-85%),而双键裂变的羰基化合物在C 8 -C 12体系中是主要产物。以高产率(85%)获得的1-己酰甘油被中链脂肪酸氯化物进一步酰化,以制备混合中链甘油三酸酯(85-90%)。因此,可以轻松制备三酰基甘油,例如C 6 -C 6 -C 6,C 6 -C 8 -C 8,C 6 -C完成10 –C 10和C 6 –C 12 –C 12。