E2 enzymes: lessons in ubiquitin transfer from XLID patients

E2 enzymes: lessons in ubiquitin transfer from XLID patients, Published online: 10 December 2018; doi:10.1038/s41589-018-0191-4

Characterization of a novel mutation in the E2 ubiquitin-conjugating enzyme UBE2A accounts for the decreased activity of the mutant enzyme that underlies disease and provides important insight into the catalytic mechanism of E2s.

中文翻译：

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E2酶：XLID患者泛素转移的经验教训

E2酶：XLID患者泛素转移的经验教训

E2酶：XLID患者泛素转移的经验教训，在线发布：2018年12月10日; doi：10.1038 / s41589-018-0191-4

E2泛素缀合酶UBE2A中新突变的表征说明了疾病基础突变酶的活性降低，并为E2s的催化机制提供了重要的见识。