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Targeting Peptide-Based Probes for Molecular Imaging and Diagnosis.
Advanced Materials ( IF 27.4 ) Pub Date : 2018-12-07 , DOI: 10.1002/adma.201804827
Weizhi Wang 1 , Zhiyuan Hu 1, 2, 3
Affiliation  

A series of novel peptide-based molecular probes for different biomarkers is highlighted herein. These probes can provide targeted recognition with high affinity, high specificity, high penetration, and rapid excretion ability. These sensitive peptides can achieve rapid and specific detection when they are conjugated with imaging moieties or are formed into nanoprobes, which can be adapted for in vivo molecular imaging in targeted diagnosis and therapy.

中文翻译:

靶向肽基探针用于分子成像和诊断。

本文重点介绍了一系列针对不同生物标志物的新型基于肽的分子探针。这些探针可提供具有高亲和力,高特异性,高穿透力和快速排泄能力的靶向识别。这些敏感的肽与成像部分缀合或形成纳米探针后,可以实现快速,特异性的检测,可将其用于靶向诊断和治疗中的体内分子成像。
更新日期:2019-11-06
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