Contributions of dsRNases to differential RNAi efficiencies between the injection and oral delivery of dsRNA in Locusta migratoria,Pest Management Science

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Contributions of dsRNases to differential RNAi efficiencies between the injection and oral delivery of dsRNA in Locusta migratoria
Pest Management Science ( IF 3.8 ) Pub Date : 2019-01-08 , DOI: 10.1002/ps.5291
Huifang Song _{1,

2} , Yunhe Fan _{1,

2} , Jianqin Zhang _{1,

3} , Anastasia MW Cooper ₄ , Kristopher Silver ₄ , Daqi Li _{1,

5} , Tao Li ₁ , Enbo Ma ₁ , Kun Yan Zhu ₄ , Jianzhen Zhang ₁

Affiliation

The efficiency of RNA interference (RNAi) varies considerably among different insect species, and there is growing evidence to suggest that degradation of double‐stranded (dsRNA) prior to uptake is an important factor that limits the efficiency of RNAi in insects. In Locusta migratoria, RNAi is highly efficient when dsRNA is delivered by injection, but not by feeding. However, detailed mechanisms causing such differential RNAi efficiency are still elusive.

中文翻译：

dsRNA酶对双侧链球菌在注射和口服dsRNA之间差异RNAi效率的贡献

不同昆虫种类之间RNA干扰（RNAi）的效率差异很大，并且越来越多的证据表明，摄取前双链（dsRNA）的降解是限制昆虫中RNAi效率的重要因素。在Locusta migratoria中，当通过注射而不是通过饲喂递送dsRNA时，RNAi的效率很高。但是，导致这种不同的RNAi效率的详细机制仍然难以捉摸。

更新日期：2019-01-08

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