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CHD2: One Gene, Many Roles.
Neuron ( IF 14.7 ) Pub Date : 2018-Dec-05 , DOI: 10.1016/j.neuron.2018.11.036
Vanesa Nieto-Estevez , Jenny Hsieh

Mutations in the chromodomain helicase DNA-binding 2 (CHD2) gene have been found in patients with a range of neurodevelopmental disorders. In this issue of Neuron, Kim et al. (2018) showed that Chd2 haploinsufficiency compromises cortical development, synaptic function, and memory in mice.

中文翻译:

CHD2:一个基因,许多角色。

在患有一系列神经发育障碍的患者中发现了染色体结构域解旋酶DNA结合2(CHD2)基因的突变。在Neuron的这一期中,Kim等人。(2018)表明Chd2单倍体不足会损害小鼠的皮质发育,突触功能和记忆。
更新日期:2018-12-06
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