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Comparing phenotypic variation between inbred and outbred mice.
Nature Methods ( IF 36.1 ) Pub Date : 2018-11-30 , DOI: 10.1038/s41592-018-0224-7 Alexander H Tuttle 1 , Vivek M Philip 2 , Elissa J Chesler 2 , Jeffrey S Mogil 3
Nature Methods ( IF 36.1 ) Pub Date : 2018-11-30 , DOI: 10.1038/s41592-018-0224-7 Alexander H Tuttle 1 , Vivek M Philip 2 , Elissa J Chesler 2 , Jeffrey S Mogil 3
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Comparing phenotypic variation between inbred and outbred mice
中文翻译：
比较近交和近交小鼠的表型变异。
比较近交和近交小鼠的表型变异
更新日期：2018-12-10
Comparing phenotypic variation between inbred and outbred mice, Published online: 30 November 2018; doi:10.1038/s41592-018-0224-7
Inbred mice are preferred over outbred mice because it is assumed that they display less trait variability. We compared coefficients of variation and did not find evidence of greater trait stability in inbred mice. We conclude that contrary to conventional wisdom, outbred mice might be better subjects for most biomedical research.中文翻译：
比较近交和近交小鼠的表型变异。
比较近交和近交小鼠的表型变异
近交和近交小鼠之间的表型变异比较，在线发布：2018年11月30日; doi：10.1038 / s41592-018-0224-7
自交小鼠优于自交小鼠，因为假定它们表现出较少的性状变异性。我们比较了变异系数，没有发现自交小鼠性状稳定性更高的证据。我们得出结论，与传统观点相反，杂种小鼠可能是大多数生物医学研究的较好对象。
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