Variable brain-specific mutations have been observed in Alzheimer’s disease. One mechanism underlying this mosaicism involves integration of variant gene copies back into the neuronal genome.Variable brain-specific mutations have been observed in Alzheimer’s disease. One mechanism underlying this mosaicism involves integration of variant gene copies back into the neuronal genome.

中文翻译：

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一种新发现的驱动阿尔茨海默病神经元突变的机制

在阿尔茨海默病中观察到了可变的大脑特异性突变。这种嵌合现象背后的一种机制涉及将变异基因拷贝整合回神经元基因组。在阿尔茨海默病中已经观察到可变的大脑特异性突变。这种镶嵌现象背后的一种机制涉及将变异基因拷贝整合回神经元基因组。