Identification of a TLR2 Inhibiting Wheat Hydrolysate,Molecular Nutrition & Food Research

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Identification of a TLR2 Inhibiting Wheat Hydrolysate
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2018-11-02 , DOI: 10.1002/mnfr.201800716
Mensiena B G Kiewiet ₁ , Renske Dekkers ₂ , Martine P van Gool ₂ , Laurien H Ulfman ₂ , Andre Groeneveld ₂ , Marijke M Faas _{1,

3} , Pau de Vos ₁

Affiliation

Wheat hydrolysates are used in medical nutrition to provide undernourished patients a readily digestible protein source, for instance to recover from chemotherapy‐induced intestinal mucosal inflammation. Since many hydrolysates of different sources can modulate the immune system, likely via Toll‐like receptors (TLRs), it is hypothesized that also wheat hydrolysates might interact with TLR signaling, which could be a way to prevent intestinal inflammation and damage.

中文翻译：

TLR2 抑制小麦水解物的鉴定

小麦水解物用于医疗营养，为营养不良的患者提供易于消化的蛋白质来源，例如从化疗引起的肠粘膜炎症中恢复。由于许多不同来源的水解产物可能通过 Toll 样受体 (TLR) 调节免疫系统，因此推测小麦水解产物也可能与 TLR 信号相互作用，这可能是预防肠道炎症和损伤的一种方法。

更新日期：2018-11-02

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