Methanol Promoted Palladium‐Catalyzed Amine Formylation with CO2 and H2 by the Formation of HCOOCH3,ChemCatChem

当前位置： X-MOL 学术 › ChemCatChem › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Methanol Promoted Palladium‐Catalyzed Amine Formylation with CO2 and H2 by the Formation of HCOOCH3
ChemCatChem ( IF 3.8 ) Pub Date : 2018-10-29 , DOI: 10.1002/cctc.201801404
Yanyan Wang _{1,

2} , Bingfeng Chen ₁ , Shulin Liu _{1,

2} , Xiaojun Shen _{1,

2} , Shaopeng Li _{1,

2} , Youdi Yang _{1,

2} , Huizhen Liu _{1,

2} , Buxing Han _{1,

2}

Affiliation

The N‐formylation reaction of amines is one of the most effective measures to make the best use of CO₂, since the formamides have widespread applications in industry. Herein, we performed the N‐formylation reaction over Mg−Al layered double hydroxide (Mg−Al LDH) supported Pd catalyst (Pd/LDH) for the first time and studied the relation between the solvent and the mechanism. In this reaction, the methanol can greatly improve the yield of the desired product by forming the HCOOCH₃. The catalytic system is effective for various amines including cyclic and alkyl secondary amines. Under the optimized reaction condition, we gained 88.5 %–97.4 % yields of the formamides for various substrates.

中文翻译：

甲醇通过HCOOCH3的形成促进钯催化的胺与CO2和H2的甲酰化反应

胺的N-甲酰化反应是最有效地利用CO ₂的最有效方法之一，因为甲酰胺在工业上具有广泛的应用。本文中，我们首次在Mg-Al层状双氢氧化物（Mg-Al LDH）负载的Pd催化剂（Pd / LDH）上进行了N-甲酰化反应，并研究了溶剂与反应机理之间的关系。在该反应中，甲醇可通过形成HCOOCH ₃大大提高所需产物的收率。该催化体系对包括环仲胺和烷基仲胺在内的各种胺是有效的。在优化的反应条件下，对于各种底物，我们获得了88.5％–97.4％的甲酰胺收率。

更新日期：2018-10-29

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南