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The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris.
Scientific Reports ( IF 3.8 ) Pub Date : 2018-Oct-08 , DOI: 10.1038/s41598-018-33199-z Klara Junker , Gustavo Bravo Ruiz , Alexander Lorenz , Louise Walker , Neil A. R. Gow , Jürgen Wendland
Scientific Reports ( IF 3.8 ) Pub Date : 2018-Oct-08 , DOI: 10.1038/s41598-018-33199-z Klara Junker , Gustavo Bravo Ruiz , Alexander Lorenz , Louise Walker , Neil A. R. Gow , Jürgen Wendland
Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, we show that the mycoparasitic yeast Saccharomycopsis schoenii efficiently kills both sensitive and multi-drug resistant isolates of C. auris belonging to the same clade, as well as clinical isolates of other pathogenic species of the Candida genus suggesting novel approaches for biocontrol.
中文翻译:
霉菌真菌酵母Schocharii早于并杀死了多药抗性假丝酵母。
最近,假丝酵母已成为一种多药耐药性真菌病原体,对全球健康构成严重威胁,尤其是对于医院重症监护病房(ICU)的患者而言。金黄色葡萄球菌可以定居在人类皮肤上,并且可以通过物理接触或受污染的表面和设备传播。在这里,我们表明,霉菌真菌酵母菌能有效杀死属于同一进化枝的金黄色葡萄球菌的敏感和多药耐药菌株,以及念珠菌属的其他病原体的临床菌株,这提示了生物防治的新方法。
更新日期:2018-10-08
中文翻译:
霉菌真菌酵母Schocharii早于并杀死了多药抗性假丝酵母。
最近,假丝酵母已成为一种多药耐药性真菌病原体,对全球健康构成严重威胁,尤其是对于医院重症监护病房(ICU)的患者而言。金黄色葡萄球菌可以定居在人类皮肤上,并且可以通过物理接触或受污染的表面和设备传播。在这里,我们表明,霉菌真菌酵母菌能有效杀死属于同一进化枝的金黄色葡萄球菌的敏感和多药耐药菌株,以及念珠菌属的其他病原体的临床菌株,这提示了生物防治的新方法。