Cornea Implants: Cyclodextrin Modulated Type I Collagen Self‐Assembly to Engineer Biomimetic Cornea Implants (Adv. Funct. Mater. 41/2018),Advanced Functional Materials

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Cornea Implants: Cyclodextrin Modulated Type I Collagen Self‐Assembly to Engineer Biomimetic Cornea Implants (Adv. Funct. Mater. 41/2018)
Advanced Functional Materials ( IF 18.5 ) Pub Date : 2018-10-08 , DOI: 10.1002/adfm.201870297
Shoumyo Majumdar _{1,

2,

3} , Xiaokun Wang _{1,

3,

4} , Sven D. Sommerfeld _{1,

3,

4} , Jemin Jeremy Chae _{1,

3,

4} , Evangelia-Nefeli Athanasopoulou ₅ , Lucas S. Shores ₃ , Xiaodong Duan ₆ , L. Mario Amzel ₇ , Francesco Stellacci ₅ , Oliver Schein ₄ , Qiongyu Guo _{3,

8} , Anirudha Singh _{1,

9} , Jennifer H. Elisseeff _{1,

2,

3,

4}

Affiliation

Corneal collagen fibrils are controlled during development by small leucine‐rich proteoglycans to create a robust, yet optically transparent tissue. In article number 1804076, Qiongyu Guo, Anirudha Singh, Jennifer H. Elisseeff, and co‐workers utilize cyclodextrins (CDs) instead to modulate fibril formation, alignment, ultrastructural organization, and spacing in vitrified collagen matrices. Access to biosynthetic cornea substitutes with advanced properties is provided. Cover iamge designed by: Caitlin Duckwall and Dhruv Majumdar.

中文翻译：

角膜植入物：环糊精调节的I型胶原蛋白自组装体，用于工程仿生角膜植入物（Adv.Funct.Mater.41 / 2018）

角膜胶原纤维在发育过程中受到富含亮氨酸的小蛋白聚糖的控制，从而形成了坚固而又光学透明的组织。在编号1804076中，郭琼玉，阿尼鲁达·辛格，詹妮弗·H·埃利斯泽夫及其同事利用环糊精（CD）来调节玻璃化胶原蛋白基质中的原纤维形成，排列，超微结构和间距。提供了具有先进性能的生物合成角膜替代品。封面图片由Caitlin Duckwall和Dhruv Majumdar设计。

更新日期：2018-10-08

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