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1,1′-Carbonyldiimidazole (CDI) Mediated Coupling and Cyclization To Generate [1,2,4]Triazolo[4,3-a]pyridines
Organic Letters ( IF 4.9 ) Pub Date : 2016-01-25 00:00:00 , DOI: 10.1021/acs.orglett.5b03589 Kyle D. Baucom 1 , Siân C. Jones 1 , Scott W. Roberts 1
Organic Letters ( IF 4.9 ) Pub Date : 2016-01-25 00:00:00 , DOI: 10.1021/acs.orglett.5b03589 Kyle D. Baucom 1 , Siân C. Jones 1 , Scott W. Roberts 1
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An operationally efficient CDI mediated tandem coupling and cyclization reaction to generate [1,2,4]triazolo[4,3-a]pyridines has been reported. The reaction conditions and scope were investigated, and the methodology was demonstrated in batch mode as well as in a continuous process.
中文翻译：
1,1'-羰基二咪唑（CDI）介导的偶联和环化反应生成[1,2,4]三唑并[4,3- a ]吡啶
已经报道了可操作有效的CDI介导的串联偶联和环化反应以生成[1,2,4]三唑并[4,3- a ]吡啶。研究了反应条件和范围，并以分批方式以及连续过程证明了该方法。
更新日期：2016-01-25
中文翻译：
1,1'-羰基二咪唑（CDI）介导的偶联和环化反应生成[1,2,4]三唑并[4,3- a ]吡啶
已经报道了可操作有效的CDI介导的串联偶联和环化反应以生成[1,2,4]三唑并[4,3- a ]吡啶。研究了反应条件和范围，并以分批方式以及连续过程证明了该方法。
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