Synthesis ( IF 2.2 ) Pub Date : 2018-08-16 , DOI: 10.1055/s-0037-1610209
Issa Yavari 1 , Aliyeh Khajeh-Khezri
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Abstract
Acenaphthylene-1,2-dione has been utilized in a wide range of reactions as a starting material for the synthesis of hetero- and carbocyclic compounds and complexes. This review provides a short summary of the recent advances in the application of acenaphthylene-1,2-dione in the synthesis of hetero- and carbocyclic systems and bioactive compounds. In addition, the applications of acenaphthylene-1,2-dione in the synthesis of spiro compounds, propellanes, and ligands in catalyst reactions, from 2002 to early 2018, are included.
1 Introduction
2 Synthesis of Spiro Compounds Employing Acenaphthylene-1,2-dione
2.1 Methods for the Construction of Spiro Compounds
2.1.1 By 1,3-Dipolar Cycloaddition of Acenaphthylene-1,2-dione via Azomethine Ylides
2.1.2 By Multicomponent Reactions of Acenaphthylene-1,2-dione with C–H Acidic Compounds
2.1.3 By Reaction of Acenaphthylene-1,2-dione with Zwitterionic Intermediates
2.1.4 By Substitution and Multicomponent Reactions of Acenaphth- ylene-1,2-dione with Different Nucleophiles
3 Synthesis of Propellanes by Employing Acenaphthylene-1,2-dione
3.1 Methods for the Construction of Propellanes Based on Acenaph- thylene-1,2-dione
3.1.1 By Reaction of Acenaphthylene-1,2-dione with Nucleophiles
3.1.2 By Reaction of Acenaphthylene-1,2-dione with Binucleophiles
4 Synthesis of Ligands Employing Acenaphthylene-1,2-dione for Catalyst Reactions
5 Synthesis of Novel Hetero- and Carbocyclic Compounds Employing Acenaphthylene-1,2-dione
5.1 By Reaction of Acenaphthylene-1,2-dione with Nucleophiles
5.2 By Reaction of Acenaphthylene-1,2-dione with Zwitterionic Intermediates
5.3 By Ring Opening and Ring Enlargement
6 Conclusion
Acenaphthylene-1,2-dione has been utilized in a wide range of reactions as a starting material for the synthesis of hetero- and carbocyclic compounds and complexes. This review provides a short summary of the recent advances in the application of acenaphthylene-1,2-dione in the synthesis of hetero- and carbocyclic systems and bioactive compounds. In addition, the applications of acenaphthylene-1,2-dione in the synthesis of spiro compounds, propellanes, and ligands in catalyst reactions, from 2002 to early 2018, are included.
1 Introduction
2 Synthesis of Spiro Compounds Employing Acenaphthylene-1,2-dione
2.1 Methods for the Construction of Spiro Compounds
2.1.1 By 1,3-Dipolar Cycloaddition of Acenaphthylene-1,2-dione via Azomethine Ylides
2.1.2 By Multicomponent Reactions of Acenaphthylene-1,2-dione with C–H Acidic Compounds
2.1.3 By Reaction of Acenaphthylene-1,2-dione with Zwitterionic Intermediates
2.1.4 By Substitution and Multicomponent Reactions of Acenaphth- ylene-1,2-dione with Different Nucleophiles
3 Synthesis of Propellanes by Employing Acenaphthylene-1,2-dione
3.1 Methods for the Construction of Propellanes Based on Acenaph- thylene-1,2-dione
3.1.1 By Reaction of Acenaphthylene-1,2-dione with Nucleophiles
3.1.2 By Reaction of Acenaphthylene-1,2-dione with Binucleophiles
4 Synthesis of Ligands Employing Acenaphthylene-1,2-dione for Catalyst Reactions
5 Synthesis of Novel Hetero- and Carbocyclic Compounds Employing Acenaphthylene-1,2-dione
5.1 By Reaction of Acenaphthylene-1,2-dione with Nucleophiles
5.2 By Reaction of Acenaphthylene-1,2-dione with Zwitterionic Intermediates
5.3 By Ring Opening and Ring Enlargement
6 Conclusion
中文翻译：
基于ena1,2-二酮的杂环和碳环化合物及配合物的合成新进展
摘要
ena1,2-二酮已被广泛用于合成杂和碳环化合物和配合物的起始反应中。这篇综述简要概述了ena-1,2-二酮在杂，碳环体系和生物活性化合物合成中的最新应用。此外，还包括2002年至2018年初of烯1,2-二酮在螺环化合物，丙炔和催化剂配体的合成中的应用。
1引言
2利用Ac1,2-二酮的螺环化合物的合成
2.1螺环化合物的构建方法
2.1.1通过偶氮甲Y叶立德By烯1,2-二酮的1,3-偶极环加成反应
2.1.2 ena1,2-二酮与CHH酸性化合物的多组分反应
2.1.3 ena1,2-二酮与两性离子中间体的反应
2.1.4 ena烯-1,2-二酮与不同亲核试剂的取代和多组分反应
3利用Ac1,2-二酮合成丙烷
3.1基于Ac-1,2-二酮的环戊烷的构建方法
3.1.1通过ena1,2-二酮与亲核试剂反应
3.1.2通过ena1,2-二酮与双亲核试剂反应
4使用Ac1,2-二酮催化反应的配体的合成
5利用Ac1,2-二酮的新型杂环和碳环化合物的合成
5.1通过ena1,2-二酮与亲核试剂反应
5.2通过ena1,2-二酮与两性离子中间体反应
5.3开环和扩环
六，结论
ena1,2-二酮已被广泛用于合成杂和碳环化合物和配合物的起始反应中。这篇综述简要概述了ena-1,2-二酮在杂，碳环体系和生物活性化合物合成中的最新应用。此外，还包括2002年至2018年初of烯1,2-二酮在螺环化合物，丙炔和催化剂配体的合成中的应用。
1引言
2利用Ac1,2-二酮的螺环化合物的合成
2.1螺环化合物的构建方法
2.1.1通过偶氮甲Y叶立德By烯1,2-二酮的1,3-偶极环加成反应
2.1.2 ena1,2-二酮与CHH酸性化合物的多组分反应
2.1.3 ena1,2-二酮与两性离子中间体的反应
2.1.4 ena烯-1,2-二酮与不同亲核试剂的取代和多组分反应
3利用Ac1,2-二酮合成丙烷
3.1基于Ac-1,2-二酮的环戊烷的构建方法
3.1.1通过ena1,2-二酮与亲核试剂反应
3.1.2通过ena1,2-二酮与双亲核试剂反应
4使用Ac1,2-二酮催化反应的配体的合成
5利用Ac1,2-二酮的新型杂环和碳环化合物的合成
5.1通过ena1,2-二酮与亲核试剂反应
5.2通过ena1,2-二酮与两性离子中间体反应
5.3开环和扩环
六，结论
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