Consume or Conserve: Microroughness of Titanium Implants toward Fabrication of Dual Micro–Nanotopography,ACS Biomaterials Science & Engineering

当前位置： X-MOL 学术 › ACS Biomater. Sci. Eng. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Consume or Conserve: Microroughness of Titanium Implants toward Fabrication of Dual Micro–Nanotopography
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2018-08-13 00:00:00 , DOI: 10.1021/acsbiomaterials.8b00829
Karan Gulati ₁ , Tao Li ₂ , Sašo Ivanovski ₁

Affiliation

Combining the microroughness of current titanium implants, which promotes accelerated bone integration, with nanotopography for enhanced bioactivity/drug-release may be an ideal solution to address therapeutic challenges inside the bone microenvironment. We hereby present single-step electrochemical anodization using conditioned electrolyte to enable fabrication of aligned titania nanopores with preserved microscale features of the underlying titanium implant. This is applicable toward the fabrication of mechanically robust and clinically translatable next-generation orthopedic/dental implants with dual-topography including “gold-standard” microroughness and superimposed “bioactive” nanotopography.

中文翻译：

消耗或保存：钛植入物的微粗糙度对双显微纳米形貌的制造

结合当前钛植入物的微观粗糙度（可促进骨骼整合加速）与纳米形貌以增强生物活性/药物释放相结合，可能是解决骨骼微环境内部治疗难题的理想解决方案。我们在此提出了使用条件电解质的单步电化学阳极氧化工艺，该工艺能够使排列的二氧化钛纳米孔具有潜在的钛植入物的微米级特征得以保留。这适用于制造具有双重形貌的机械坚固且可临床翻译的下一代骨科/牙科植入物，包括“金标准”微粗糙度和叠加的“生物活性”纳米形貌。

更新日期：2018-08-13

点击分享查看原文

点击收藏

公开下载

阅读更多本刊新发论文本刊介绍/投稿指南