DBU-Catalyzed Desymmetrization of Cyclohexadienones: Access to Vicinal Diamine-Containing Heterocycles,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

DBU-Catalyzed Desymmetrization of Cyclohexadienones: Access to Vicinal Diamine-Containing Heterocycles
Organic Letters ( IF 4.9 ) Pub Date : 2018-08-03 00:00:00 , DOI: 10.1021/acs.orglett.8b02158
Hongxing Jin ₁ , Changhang Dai ₁ , You Huang _{1,

2}

Affiliation

A DBU-catalyzed desymmetrization strategy between cyclohexadienones and isocyanates was discovered, affording a series of vicinal diamine-containing heterocycle derivatives in moderate to good yields and excellent diastereoselectivity under mild conditions. Furthermore, this reaction could be performed on a 10 g scale using 1.0 mol % of catalyst loading.

中文翻译：