A one-pot procedure for the synthesis of 5-benzoyl-8H-phthalazino[1,2-b]quinazolin-8-ones is achieved by an iodine-catalyzed reaction of 2-aminobenzohydrazides and 2-alkynylbenzaldehydes in good yields. The salient feature of this strategy is a domino type process including a condensation, addition, hydroamination, and a noteworthy benzyl automatic oxidation by oxygen under metal-catalyst-free conditions.

中文翻译：

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碘通过涉及氧的苄基自动氧化的多米诺反应，碘催化合成5-苯甲酰基-8 H-酞嗪[1,2 - b ]喹唑啉-8-衍生物

通过碘催化的2-氨基苯甲酰肼和2-炔基苯甲醛的高产率合成一锅法合成5-苯甲酰基-8 H-酞嗪并[1,2 - b ]喹唑啉-8-酮。该策略的显着特征是多米诺骨牌型工艺，包括缩合，加成，加氢胺化以及在无金属催化剂的条件下通过氧气进行的引人注目的苄基自动氧化。