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Stereoselective synthesis of (E,Z)-3,4-dialkylidene-N-phenylpyrrolidine-2,5-diones starting from Morita–Baylis–Hillman carbonates
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2016-01-01 08:03:21
Ko Hoon Kim, Su Yeon Kim, Ji Yeon Ryu, Junseong Lee, Jae Nyoung Kim

An efficient stereoselective synthesis of (E,Z)-3,4-dialkylidene-N-phenylpyrrolidine-2,5-diones from Morita–Baylis–Hillman carbonates and phenyl isocyanate has been developed. Synthetic usefulness of the compounds has been demonstrated by the preparation of 2,4,5-triphenylisoindole-1,3-diones and N-phenylbenzo[f]isoindole-1,3-dione derivatives.

中文翻译:

从森田-贝利斯-希尔曼碳酸盐开始的立体选择性合成(E,Z)-3,4-二亚烷基-N-苯基吡咯烷-2,5-二酮

已经开发了由森田-贝利斯-希尔曼碳酸盐和异氰酸苯酯合成(E,Z)-3,4-二亚烷基-N-苯基吡咯烷-2,5-二酮的有效立体选择性合成方法。通过制备2,4,5-三苯基异吲哚-1,3-二酮和N-苯基苯并[f]异吲哚-1,3-二酮衍生物已证明了该化合物的合成用途。
更新日期:2016-01-02
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