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Nanohybrids: Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles, and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics (Adv. Mater. 24/2018)
Advanced Materials ( IF 27.4 ) Pub Date : 2018-06-08 , DOI: 10.1002/adma.201870168
Zehua Liu 1 , Yunzhan Li 2, 3 , Wei Li 1 , Chen Xiao 2, 3 , Dongfei Liu 1, 4 , Chao Dong 2, 3 , Ming Zhang 2, 3 , Ermei Mäkilä 5 , Marianna Kemell 6 , Jarno Salonen 5 , Jouni T. Hirvonen 1 , Hongbo Zhang 7, 8 , Dawang Zhou 2, 3 , Xianming Deng 2, 3 , Hélder A. Santos 1, 4
Affiliation  

A nanohybrid based on porous silicon (PSi) nanoparticles, gold nanoparticles, and acetalated dextran is designed for acute liver failure (ALF) reversal and CT‐imaging‐facilitated ALF indication. In article number 1703393, Hongbo Zhang, Dawang Zhou, Xianming Deng, Hélder A. Santos, and co‐workers develop a PSi‐based nanohybrid composite for liver regeneration and ALF treatment. This system is used to identify pathological changes in the tissues and selectively deliver drugs to these sites, facilitating imaging in vivo, and is thus a great potential theranostic platform for ALF.
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中文翻译:

纳米杂化物:基于多孔硅纳米粒子,金纳米粒子和乙酰化葡聚糖的多功能纳米杂化物,可用于肝脏再生和急性肝衰竭治疗学(Adv.Mater.24 / 2018)

基于多孔硅(PSi)纳米颗粒,金纳米颗粒和乙缩醛右旋糖酐的纳米杂交体旨在用于急性肝衰竭(ALF)逆转和CT成像辅助的ALF适应症。在编号1703393中,张洪波,周大旺,邓宪明,HélderA. Santos及其同事开发了一种基于PSi的纳米杂化复合材料,用于肝脏再生和ALF治疗。该系统用于识别组织中的病理变化,并选择性地将药物递送至这些部位,从而促进体内成像,因此是ALF的巨大治疗学平台。
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更新日期:2018-06-08
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