A practical, operationally simple preparation of 2-(trimethylsilyl)methyl-2-propen-1-ol derivatives is described. The cobalt catalyzed coupling of a protected vinyl halide with trimethylsilylmethylmagnesium chloride shows excellent functional group tolerance and provides these synthetically useful allyl silanes in good overall yield. By this method, the use of highly concentrated organolithium reagents, complex reaction protocols, and expensive starting materials is avoided.

中文翻译：

---

钴催化的sp2-sp3偶联制备2-（三甲基甲硅烷基）甲基-2-丙烯-1-醇衍生物

描述了一种实用，操作上简单的2-（三甲基甲硅烷基）甲基-2-丙烯-1-醇衍生物的制备方法。受保护的乙烯基卤化物与三甲基甲硅烷基甲基氯化镁的钴催化偶联显示出优异的官能团耐受性，并以良好的总产率提供了这些合成上有用的烯丙基硅烷。通过这种方法，可以避免使用高浓度的有机锂试剂，复杂的反应方案以及昂贵的起始原料。