A C₂-symmetric, chiral bis-cyclosulfinamide-olefin ligand composed of two 1-oxo-2,3-dihydro-1,2-benzisothiazole moieties with rigid skeletons and a conformationally flexible butenylene chain is disclosed for the first time. HRMS and ¹H NMR analyses verify that the in situ-generated complex of the ligand and [Rh(C₂H₄)₂Cl]₂ possesses a rhodium (I) center coordinated to the tridentate ligand via two sulfinyl moieties and a CdbndC bond. The chiral ligand provided extremely high enantioselectivity (up to >99%ee) in the Rh-catalyzed asymmetric 1,4-additions of arylboronic acids to cyclohexenone and cyclopentenone. The tridentate ligand gave much higher enantioselectivity than the analogous chiral bidentate ligands.

首次公开了由两个具有刚性骨架和构象柔性的丁烯链的1-氧代-2，3-二氢-1，2-苯并噻唑结构部分组成的AC ₂对称的手性双环亚磺酰胺-烯烃配体。HRMS和¹ H NMR分析证实，该配体与[Rh（C ₂ H ₄）₂ Cl] ₂原位生成的络合物具有通过两个亚磺酰基部分和一个CdbndC键与三齿配体配位的铑（I）中心。手性配体在Rh催化的芳基硼酸与环己烯酮和环戊烯酮的不对称1,4-加成反应中提供了极高的对映选择性（高达> 99％ee）。与类似的手性二齿配体相比，三齿配体具有更高的对映选择性。