A novel difunctionalization reaction is described. It uses N-trifluoromethylthio-4-nitrophthalimide as the reagent, which serves as both the nitrogen and SCF₃ sources. In the presence of DABCO (1,4-diazabicyclo[2.2.2]octane), the nitrogen and SCF₃ groups can be incorporated into α,β-unsaturated carbonyl compounds easily and give versatile β-amino ketones and esters in good yields. This difunctionalization reaction features mild reaction conditions, high atom-economy, and efficient access to α-SCF₃ amino acids.

中文翻译：

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1,4-二氮杂双环[2.2.2]辛烷促进的α，β-不饱和羰基化合物的氨基三氟甲基硫醇化：N-三氟甲基硫基-4-硝基邻苯二甲酰亚胺同时充当氮和SCF _3的来源

描述了新的双官能化反应。它使用N-三氟甲基硫基-4-硝基邻苯二甲酰亚胺作为试剂，既用作氮源，又用作SCF ₃源。在DABCO（1,4-二氮杂双环[2.2.2]辛烷）的存在下，氮和SCF ₃基团可以轻松地掺入α，β-不饱和羰基化合物中，并以良好的收率得到通用的β-氨基酮和酯。此difunctionalization反应设有反应条件温和，高原子经济性，并且α-SCF高效访问₃个氨基酸。