New Antimicrobial Cyclopentenones from Nigrospora sphaerica ZMT05, a Fungus Derived from Oxya chinensis Thunber,Journal of Agricultural and Food Chemistry

当前位置： X-MOL 学术 › J. Agric. Food Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

New Antimicrobial Cyclopentenones from Nigrospora sphaerica ZMT05, a Fungus Derived from Oxya chinensis Thunber
Journal of Agricultural and Food Chemistry ( IF 5.7 ) Pub Date : 2018-05-10 00:00:00 , DOI: 10.1021/acs.jafc.8b01376
Zhihui Wu ₁ , Zihui Xie ₁ , Manlin Wu ₁ , Xiaoqi Li ₁ , Weilin Li ₁ , Weijia Ding ₁ , Zhigang She ₂ , Chunyuan Li ₁

Affiliation

Six new cyclopentenone derivatives (+)-nigrosporione A (+)-1, (−)-nigrosporione A (−)-1, nigrosporione B (2), nigrosporione C (3), (+)-nigrosporione D (+)-4, and (−)-nigrosporione D (−)-4 were isolated from an endophytic fungus Nigrospora sphaerica ZMT05, collected from the rice grasshopper (Oxya chinensis Thunberg), which is an insect pest in rice and which is also used as a food for people in some countries. Their planar and spatial structures were determined by spectroscopic analyses and eletronic circular dichroism (ECD) calculations. Compounds (+)-1, (−)-1, and 2 inhibited the plant pathogens Fusarium oxysporum, Colletotrichum musae, Penicillium italicum, and Fusarium graminearum, compounds 3 and (−)-4 inhibited F. oxysporum, C. musae, and P. italicum, and compound (+)-4 inhibited F. oxysporum, C. musae, and F. graminearum, showing antifungal activities stronger than triadimefon. Additionally, compounds (+)-1, (−)-1, 2, and 3 displayed moderate antibacterial activities against Staphyloccocus aureus and Escherichia coli.

中文翻译：

一种来自Nigrospora sphaerica ZMT05的新型抗菌环戊烯酮，它是一种来自Oxya chinensis Thunber的真菌

六个新的环戊烯酮衍生物（+）-黑孢子酮A（+）- 1，（-）-黑孢子酮A（-）- 1，黑孢子酮B（2），黑孢子酮C（3），（+）-黑孢子酮D（+）- 4和（-）-黑孢子酮D（-）- 4是从内生真菌Nigrospora sphaerica ZMT05中分离出来的，该内生真菌是从稻蝗（Oxya chinensis Thunberg）收集的，后者是水稻中的一种害虫，也被用作食品。适用于某些国家/地区的人们。它们的平面和空间结构是通过光谱分析和电子圆二色性（ECD）计算确定的。化合物（+）- 1，（-）- 1和2抑制植物病原体尖镰刀菌，炭疽菌，青霉和禾谷镰刀菌，化合物3和（-）- 4抑制尖孢镰刀菌，mus。musae和P. italicum，化合物（+）- 4抑制尖孢镰刀菌。，C。musae和F. graminearum，显示出比三唑酮更强的抗真菌活性。此外，化合物（+） - 1，（ - ） - 1，2，和3对金黄色葡萄球菌和大肠杆菌表现出中等的抗菌活性。

更新日期：2018-05-10

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南