Cover Feature: Clickable Polyamine Derivatives as Chemical Probes for the Polyamine Transport System (ChemBioChem 9/2018),ChemBioChem

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Cover Feature: Clickable Polyamine Derivatives as Chemical Probes for the Polyamine Transport System (ChemBioChem 9/2018)
ChemBioChem ( IF 2.6 ) Pub Date : 2018-04-19 , DOI: 10.1002/cbic.201800190
Roeland Vanhoutte ₁ , Jan Pascal Kahler ₁ , Shaun Martin ₂ , Sarah van Veen ₂ , Steven H. L. Verhelst _{1,

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Affiliation

The cover feature picture shows how an azido‐functionalized polyamine, clicked to a fluorphore, can be used as a tool to hijack the polyamine transport system (PTS). This opens the way to selectively deliver the fluorphore cargo into cancer cells, but not to non‐cancerous cells, which have lower activity of the PTS. More information can be found in the communication by S. H. L. Verhelst et al. on page 907 in Issue 9, 2018 (DOI: 10.1002/cbic.201800043).

中文翻译：

封面功能：可点击的多胺衍生物作为多胺传输系统的化学探针（ChemBioChem 9/2018）

封面特征图片显示了如何将叠氮基官能化的多胺单击荧光，用作劫持多胺运输系统（PTS）的工具。这为选择性地将荧光物质输送到癌细胞中，而不是输送到具有较低PTS活性的非癌细胞中开辟了道路。S.H.L.Verhelst等人在来文中可以找到更多信息。就在第9期，2018页907（：10.1002 / cbic.201800043 DOI）。

更新日期：2018-04-19

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