Reptiles are the most morphologically and physiologically diverse tetrapods, and have undergone 300 million years of adaptive evolution. Within the reptilian tetrapods, geckos possess several interesting features, including the ability to regenerate autotomized tails and to climb on smooth surfaces. Here we sequence the genome of Gekko japonicus (Schlegel's Japanese Gecko) and investigate genetic elements related to its physiology. We obtain a draft G. japonicus genome sequence of 2.55 Gb and annotated 22,487 genes. Comparative genomic analysis reveals specific gene family expansions or reductions that are associated with the formation of adhesive setae, nocturnal vision and tail regeneration, as well as the diversification of olfactory sensation. The obtained genomic data provide robust genetic evidence of adaptive evolution in reptiles.

中文翻译：

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Gekko japonicus基因组揭示了脚趾脚垫的进化和尾巴的再生。

爬行动物是形态和生理上最多样化的四足动物，已经经历了3亿年的适应性进化。在爬虫类四足动物中，壁虎具有几个有趣的特征，包括能够再生自动切尾的尾巴并能在光滑的表面上爬升的能力。在这里，我们对日本壁虎的基因组进行了测序，并研究了与其生理相关的遗传因素。我们获得了2.55 Gb和注释的22,487个基因的日本粳稻基因组序列草案。比较基因组分析揭示了特定的基因家族扩展或减少，这与粘着性刚毛的形成，夜间视力和尾巴再生以及嗅觉的多样化有关。获得的基因组数据为爬行动物的适应性进化提供了强有力的遗传证据。