In the article titled, “Vitamin K and the Prevention of Fractures: Systematic Review and Meta-analysis of Randomized Controlled Trials,”¹ published in the December 2006 print issue of Archives of Internal Medicine, conclusions were based on data from trials that have since been indicated as problematic or retracted. Seven of 13 articles included in the meta-analysis reported fracture data, and of the 7 articles that reported fracture data, 3 articles were from a single center; the data from the trials from this center have since been found to be problematic or retracted. Because 3 articles provided data from a single center, the authors performed a sensitivity analysis in the original meta-analysis, and those data were included in Figure 4. Results from the sensitivity analysis have been added to the abstract of the original article,¹ and the authors request that readers only take into account the data presented in Figure 4. A Letter of Explanation² has also been published for further clarification.

我ñ标题的文章，“维生素K和骨折的预防：系统评价和随机对照试验的荟萃分析，” ¹发表在2006年12月打印问题内科医学档案，结论是根据试验数据得出的，此后数据被认为是有问题的或已撤回。荟萃分析中的13篇文章中有7篇报道了骨折数据，在7篇报道了骨折数据的文章中，有3篇来自同一中心。此后，来自该中心的试验数据被发现存在问题或被撤回。由于3篇文章提供了来自同一中心的数据，因此作者在原始的Meta分析中进行了敏感性分析，这些数据包括在图4中。敏感性分析的结果已添加到原始文章的摘要中¹和作者要求读者仅考虑图4中显示的数据。解释信² 也已发布以进一步澄清。