当前位置:
X-MOL 学术
›
J. Saudi Chem. Soc.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
A novel synthesis of 2,5-di-substituted pyridine derivatives by the ring opening and closing cascade (ROCC) mechanism
Journal of Saudi Chemical Society ( IF 5.8 ) Pub Date : 2019-06-01 , DOI: 10.1016/j.jscs.2019.05.008 K. Raghavulu , M. Sambaiah , Ramakrishna Gudipati , K. Basavaiah , Satyanarayana Yennam , Manoranjan Behera
中文翻译:
通过开环和闭环级联(ROCC)机理的2,5-二取代吡啶衍生物的新型合成
更新日期:2019-06-01
Journal of Saudi Chemical Society ( IF 5.8 ) Pub Date : 2019-06-01 , DOI: 10.1016/j.jscs.2019.05.008 K. Raghavulu , M. Sambaiah , Ramakrishna Gudipati , K. Basavaiah , Satyanarayana Yennam , Manoranjan Behera
A new regioselective method for the synthesis of 2-aryl-5-benzoylpyridine derivatives has been developed. The reaction proceeds via ring opening and closing cascade mechanism (ROCC) of isoxazole to synthesize various functionalized pyridine derivatives. This is the first report for the preparation of 2,5-di-substituted pyridines using Fe/NH4Cl as a reducing reagent.
中文翻译:
通过开环和闭环级联(ROCC)机理的2,5-二取代吡啶衍生物的新型合成
已经开发了用于合成2-芳基-5-苯甲酰基吡啶衍生物的新的区域选择性方法。该反应通过异恶唑的开环和闭环级联机理(ROCC)进行,以合成各种官能化的吡啶衍生物。这是使用Fe / NH 4 Cl作为还原剂制备2,5-二取代吡啶的首次报道。