Astrocytes are the principal homeostatic cells of the central nerves system (CNS) that support the CNS function at all levels of organisation, from molecular to organ. Several fundamental homeostatic functions of astrocytes are mediated through plasmalemmal pumps and transporters; most of which are also regulated by the transplasmalemmal gradient of Na+ ions. Neuronal activity as well as mechanical or chemical stimulation of astrocytes trigger plasmalemmal Na+ fluxes, which in turn generate spatio-temporally organised transient changes in the cytosolic Na+ concentration, which represent the substrate of astroglial Na+ signalling. Astroglial Na+ signals link and coordinate neuronal activity and CNS homeostatic demands with the astroglial homeostatic response.

中文翻译：

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Na +依赖性转运蛋白：星形胶质稳态功能的骨干。

星形胶质细胞是中枢神经系统（CNS）的主要稳态细胞，在分子到器官的所有组织水平上均支持CNS的功能。星形胶质细胞的几种基本稳态功能是通过质膜泵和转运蛋白介导的。其中大多数也受Na +离子跨血浆梯度的调节。星形胶质细胞的神经元活动以及机械或化学刺激会触发质膜Na +通量，进而在胞浆中Na +浓度产生时空组织的瞬时变化，这代表星形胶质Na +信号的底物。星形胶质细胞Na +信号与星形胶质细胞稳态反应联系并协调神经元活动和中枢神经系统稳态需求。