An efficient protocol for Huisgen-click reaction catalyzed by Cu(OAc)2·H2O for the synthesis of 1,4-disubstituted triazoles has been developed in supercritical carbon dioxide (scCO2) in the absence of ligand at 36°C. The protocol could afford the corresponding products in excellent yield at very low catalyst loadings (0.01mol%).

中文翻译：

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Cu（OAc）2·H2O—超临界二氧化碳中惠斯根点击反应的高效催化剂

在36°C下不存在配体的情况下，在超临界二氧化碳（scCO2）中，开发了一种由Cu（OAc）2·H2O催化的用于合成1,4-二取代三唑的Huisgen-click反应的有效方案。该方案可以在非常低的催化剂负载量（0.01mol％）下以优异的产率提供相应的产物。