As an important endogenous signal molecule, abnormal levels of H₂S are closely related with many diseases. Although numerous H₂S-specific fluorescent probes have been designed, most of them have some limitations including synthetic complexity, short emission wavelength, restricted applications. In this work, a simple H₂S selective fluorescent probe (L) has been designed and synthesized by two-step reactions using 4-diethylaminosalicylaldehyde and 1,4-dimethylpyridinium iodide as raw materials. Probe L displays high selectivity and sensitivity to H₂S in DMF/H₂O (4/6, v/v, HEPES, 10 mM, pH = 7.4) with a long-wavelength emission, a large Stokes shift, and good anti-interference ability. The practical applicabilities of probe L to detect H₂S were evaluated in actual water samples, wine samples, and living cells. Moreover, the L-doped polylactic acid (PLA) nanofibrous film prepared by electrospinning can be used to detect H₂S gas.

作为重要的内源性信号分子，H ₂ S的异常水平与许多疾病密切相关。尽管已经设计了许多H ₂ S特异性荧光探针，但大多数探针都有一些局限性，包括合成复杂性，发射波长短，应用受限。本文以4-二乙基氨基水杨醛和1,4-二甲基碘化碘为原料，通过两步反应设计合成了一种简单的H ₂ S选择性荧光探针（L）。探针L在DMF / H _2中显示出对H ₂ S的高选择性和敏感性O（4/6，v / v，HEPES，10 mM，pH = 7.4）具有长波长发射，大的斯托克斯位移和良好的抗干扰能力。在实际的水样，葡萄酒样品和活细胞中评估了探针L检测H ₂ S的实际适用性。而且，通过电纺丝制备的L掺杂的聚乳酸（PLA）纳米纤维膜可以用于检测H ₂ S气体。