Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
In Vivo Electrochemical Sensors for Neurochemicals: Recent Update.
ACS Sensors ( IF 8.2 ) Pub Date : 2019-11-25 , DOI: 10.1021/acssensors.9b01713 Cong Xu 1, 2 , Fei Wu 1, 2 , Ping Yu 1, 2 , Lanqun Mao 1, 2
ACS Sensors ( IF 8.2 ) Pub Date : 2019-11-25 , DOI: 10.1021/acssensors.9b01713 Cong Xu 1, 2 , Fei Wu 1, 2 , Ping Yu 1, 2 , Lanqun Mao 1, 2
Affiliation
|
In vivo electrochemical sensing based on implantable microelectrodes is a strong driving force of analytical neurochemistry in brain. The complex and dynamic neurochemical network sets stringent standards of in vivo electrochemical sensors including high spatiotemporal resolution, selectivity, sensitivity, and minimized disturbance on brain function. Although advanced materials and novel technologies have promoted the development of in vivo electrochemical sensors drastically, gaps with the goals still exist. This Review mainly focuses on recent attempts on the key issues of in vivo electrochemical sensors including selectivity, tissue response and sensing reliability, and compatibility with electrophysiological techniques. In vivo electrochemical methods with bare carbon fiber electrodes, of which the selectivity is achieved either with electrochemical techniques such as fast-scan cyclic voltammetry and differential pulse voltammetry or based on the physiological nature will not be reviewed. Following the elaboration of each issue involved in in vivo electrochemical sensors, possible solutions supported by the latest methodological progress will be discussed, aiming to provide inspiring and practical instructions for future research.
中文翻译：
用于神经化学物质的体内电化学传感器：最新更新。
基于可植入微电极的体内电化学传感是大脑中分析神经化学的强大驱动力。复杂而动态的神经化学网络为体内电化学传感器设定了严格的标准，包括高时空分辨率，选择性，灵敏度以及对脑功能的干扰最小。尽管先进的材料和新颖的技术极大地促进了体内电化学传感器的发展，但与目标的差距仍然存在。这篇综述主要集中在关于体内电化学传感器关键问题的最新尝试，包括选择性，组织响应和传感可靠性以及与电生理技术的兼容性。使用裸碳纤维电极的体内电化学方法，其中通过电化学技术如快速扫描循环伏安法和差分脉冲伏安法实现选择性的方法，或基于生理性质的方法都将不予评论。详细阐述了体内电化学传感器涉及的每个问题之后，将讨论最新方法学进展所支持的可能解决方案，旨在为将来的研究提供启发和实践指导。
更新日期：2019-11-28
中文翻译：
用于神经化学物质的体内电化学传感器：最新更新。
基于可植入微电极的体内电化学传感是大脑中分析神经化学的强大驱动力。复杂而动态的神经化学网络为体内电化学传感器设定了严格的标准，包括高时空分辨率，选择性，灵敏度以及对脑功能的干扰最小。尽管先进的材料和新颖的技术极大地促进了体内电化学传感器的发展，但与目标的差距仍然存在。这篇综述主要集中在关于体内电化学传感器关键问题的最新尝试，包括选择性，组织响应和传感可靠性以及与电生理技术的兼容性。使用裸碳纤维电极的体内电化学方法，其中通过电化学技术如快速扫描循环伏安法和差分脉冲伏安法实现选择性的方法，或基于生理性质的方法都将不予评论。详细阐述了体内电化学传感器涉及的每个问题之后，将讨论最新方法学进展所支持的可能解决方案，旨在为将来的研究提供启发和实践指导。
京公网安备 11010802027423号