Metal-organic frameworks (MOFs) materials show great potential in wastewater separation applications. In this study, zirconium-based MOFs (UiO-66) were prepared and constructed universal, high-performance, and flexible nanofiltration (NF) membrane for various dyes and antibiotics separation. The substrate was constructed by two-steps, a) doping graphene oxide (GO) sheets into the membrane casting solution containing polyacrylonitrile (PAN) and forming 2D-3D connecting pores by phase immersion conversion method (defined as GO@PAN), b) immersing the GO@PAN substrate into dopamine solution to self-polymerize into chain macromolecules, which obtaining good compatible and flexible substrate (defined as PGP). Moreover, the UiO-66 was synthesized via solvothermal method and subsequently coated onto the PGP substrate by vacuum-assisted filtration. Benefiting from the water stability, porous structure, and negative charge of UiO-66, the outstanding filtration performance of the UiO-66/PGP thin-film composite (TFC) membrane was achieved. The pure water permeability of the UiO-66/PGP TFC membrane was 31.33 ± 0.75 L m⁻²h⁻¹ bar⁻¹, and the rejection rates for dye (Congo red, Methyl orange, Rhodamine B, and Methylene blue) and antibiotic (Tetracycline hydrochloride, Oxytetracycline, and Ciprofloxacin) were above 94%. Therefore, we further explored the retention mechanism of the UiO-66/PGP TFC membrane for dye and antibiotic separation (size exclusion and electrostatic interaction). More importantly, antifouling properties and long-time stability of the UiO-66/PGP TFC membrane were also evaluated. These results indicated that the prepared UiO-66/PGP TFC membrane is promising for wastewater treatment, separation, and purification in many industrial and pharmaceutical fields.

金属有机框架（MOF）材料在废水分离应用中显示出巨大潜力。在这项研究中，制备了基于锆的MOF（UiO-66），并构建了通用的，高性能的，灵活的纳滤（NF）膜，用于各种染料和抗生素的分离。通过两步构造基板：a）将氧化石墨烯（GO）片掺杂到包含聚丙烯腈（PAN）的膜流延溶液中，并通过相浸转换法（定义为GO @ PAN）形成2D-3D连接孔，b）将GO @ PAN底物浸入多巴胺溶液中以自聚合成链状大分子，从而获得良好的相容性和柔性底物（定义为PGP）。此外，通过溶剂热法合成UiO-66，然后通过真空辅助过滤将其涂覆在PGP基材上。受益于UiO-66的水稳定性，多孔结构和负电荷，UiO-66 / PGP薄膜复合（TFC）膜具有出色的过滤性能。UiO-66 / PGP TFC膜的纯水渗透率为31.33±0.75 L m^-2 h ^-1  bar ^-1，染料（刚果红，甲基橙，若丹明B和亚甲基蓝）和抗生素（盐酸四环素，土霉素和环丙沙星）的排斥率均高于94％。因此，我们进一步探讨了UiO-66 / PGP TFC膜用于染料和抗生素分离（尺寸排阻和静电相互作用）的保留机理。更重要的是，还评估了UiO-66 / PGP TFC膜的防污性能和长期稳定性。这些结果表明，制备的UiO-66 / PGP TFC膜有望用于许多工业和制药领域的废水处理，分离和纯化。