网络成瘾和功能性大脑网络：与任务相关的功能磁共振成像研究。,Scientific Reports

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网络成瘾和功能性大脑网络：与任务相关的功能磁共振成像研究。
Scientific Reports ( IF 3.8 ) Pub Date : 2019-10-31 , DOI: 10.1038/s41598-019-52296-1
Gergely Darnai _{1,

2,

3} , Gábor Perlaki _{3,

4,

5} , András N Zsidó ₁ , Orsolya Inhóf ₁ , Gergely Orsi _{3,

4,

5} , Réka Horváth ₂ , Szilvia Anett Nagy _{3,

4,

5,

6} , Beatrix Lábadi ₁ , Dalma Tényi ₂ , Norbert Kovács _{2,

3} , Tamás Dóczi _{3,

5} , Zsolt Demetrovics ₇ , József Janszky _{2,

3}

Affiliation

成瘾的一个与大脑有关的常见特征是高阶大脑网络功能的改变。越来越多的证据表明，与互联网相关的成瘾也与功能性大脑网络的崩溃有关。考虑到以前在网络成瘾（IA）研究中使用的研究数量有限，我们的目的是研究IA在默认模式网络（DMN）和抑制控制网络（ICN）中的功能相关性。为了观察这些关系，在60名健康的大学生中测量了与任务相关的功能磁共振成像对口头Stroop和非言语Stroop样任务的反应。有问题的互联网使用调查表（PIUQ）用于评估IA。我们发现与DMN（precuneus，后扣带回），这些区域在不一致的刺激下与PIUQ呈负相关。在Stroop任务中，incongruent_minus_congruent对比在与ICN相关的区域（左下额回，左额极，左中央小眼，左额小眼，左额眶和左小岛皮层）与PIUQ呈正相关。改变的DMN可能解释某些合并症，并可能预测治疗结果，而改变的ICN可能是难以阻止和控制过度使用的原因。

"点击查看英文标题和摘要"

Internet addiction and functional brain networks: task-related fMRI study.

A common brain-related feature of addictions is the altered function of higher-order brain networks. Growing evidence suggests that Internet-related addictions are also associated with breakdown of functional brain networks. Taking into consideration the limited number of studies used in previous studies in Internet addiction (IA), our aim was to investigate the functional correlates of IA in the default mode network (DMN) and in the inhibitory control network (ICN). To observe these relationships, task-related fMRI responses to verbal Stroop and non-verbal Stroop-like tasks were measured in 60 healthy university students. The Problematic Internet Use Questionnaire (PIUQ) was used to assess IA. We found significant deactivations in areas related to the DMN (precuneus, posterior cingulate gyrus) and these areas were negatively correlated with PIUQ during incongruent stimuli. In Stroop task the incongruent_minus_congruent contrast showed positive correlation with PIUQ in areas related to the ICN (left inferior frontal gyrus, left frontal pole, left central opercular, left frontal opercular, left frontal orbital and left insular cortex). Altered DMN might explain some comorbid symptoms and might predict treatment outcomes, while altered ICN may be the reason for having difficulties in stopping and controlling overuse.

更新日期：2019-11-01

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