We present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The brain specimen was donated by a 58-year-old woman who had no history of neurological disease and died of non-neurological causes. After fixation in 10% formalin, the specimen was imaged on a 7 Tesla MRI scanner at 100 µm isotropic resolution using a custom-built 31-channel receive array coil. Single-echo multi-flip Fast Low-Angle SHot (FLASH) data were acquired over 100 hours of scan time (25 hours per flip angle), allowing derivation of synthesized FLASH volumes. This dataset provides an unprecedented view of the three-dimensional neuroanatomy of the human brain. To optimize the utility of this resource, we warped the dataset into standard stereotactic space. We now distribute the dataset in both native space and stereotactic space to the academic community via multiple platforms. We envision that this dataset will have a broad range of investigational, educational, and clinical applications that will advance understanding of human brain anatomy in health and disease.

我们提出了离体人脑样本的超高分辨率 MRI 数据集。大脑标本由一名58岁女性捐献，她没有神经系统疾病史，死于非神经系统原因。在 10% 福尔马林中固定后，使用定制的 31 通道接收阵列线圈在 7 特斯拉 MRI 扫描仪上以 100 µm 各向同性分辨率对样本进行成像。单回波多翻转快速低角度 SHot (FLASH) 数据在 100 小时的扫描时间内获取（每个翻转角度 25 小时），从而可以推导合成的 FLASH 体积。该数据集提供了人脑三维神经解剖学的前所未有的视图。为了优化该资源的效用，我们将数据集扭曲到标准立体定向空间中。我们现在通过多个平台将本地空间和立体定向空间的数据集分发给学术界。我们预计该数据集将具有广泛的研究、教育和临床应用，这将促进对健康和疾病方面的人脑解剖学的理解。