A 56-day trial was conducted to elucidate the bioconcentration and depuration of Cd in the liver and muscle of rare minnow (Gobiocypris rarus) and determine the effect of dietary mulberry leaf supplementation on depuration. Juvenile rare minnow were exposed to environmentally relevant doses of Cd (1 and 10 μg/L) for 28 days of uptake and then allowed 28 days of depuration. The bioaccumulation factors of the treated rare minnow in the liver and muscle were calculated to be between 4.13–4.675 and 1.76–1.94, respectively. This results suggested that Cd had high potential for bioconcentration in rare minnow. To investigate the effect of dietary mulberry leaf supplementation on depuration, the remaining fish of each group were allowed to depurate with different ratios (0%, 10%, and 30% dry weight) of dietary mulberry leaf supplementation for an additional 28 days. Fish weights did not differ significantly (p > 0.05) between the control and mulberry leaf treated groups. Mulberry leaf powder did not significantly affect Cd depuration in the 10 μg/L group or in the muscle of the 1 μg/L group, but caused a significant decrease in Cd content in the liver of the 1 μg/L group (p < 0.05). This work was the first to model the bioconcentration of Cd in rare minnow and showed that mulberry leaf supplementation decreased Cd residues in the liver of the 1μg/L group. Such a finding may promote the development of new approaches to mitigate the potential hazards of heavy metals to human health.

进行了为期56天的试验，以阐明稀有min鱼（Gobiocypris rarus）肝脏和肌肉中Cd的生物浓缩和净化），并确定补充膳食的桑叶对纯净的影响。将少年稀有min鱼暴露于环境相关剂量的Cd（1和10μg/ L）中，使其摄取28天，然后进行28天的净化。经计算，处理过的稀有鲤鱼在肝脏和肌肉中的生物蓄积系数分别在4.13–4.675和1.76–1.94之间。该结果表明，镉在稀有的now鱼中具有很高的生物富集潜力。为了研究膳食桑叶补充剂对纯净度的影响，允许每组剩余的鱼以不同比例（膳食干叶补充量的0％，10％和30％干重）进行纯净，持续另外28天。鱼的重量没有显着差异（p > 0.05）在对照组和桑叶处理组之间。桑叶粉未对10μg/ L组或1μg/ L组的肌肉中的Cd净化产生显着影响，但导致1μg/ L组的肝脏中Cd含量显着降低（p  <0.05 ）。这项工作是首次模拟稀有min鱼中Cd的生物浓度，并表明补充桑叶可降低1μg/ L组肝脏中的Cd残留。这一发现可能会促进新方法的开发，以减轻重金属对人体健康的潜在危害。