Adaptive Polymeric Assemblies for Applications in Biomimicry and Nanomedicine.,Biomacromolecules

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Adaptive Polymeric Assemblies for Applications in Biomimicry and Nanomedicine.
Biomacromolecules ( IF 5.5 ) Pub Date : 2019-10-31 , DOI: 10.1021/acs.biomac.9b01341
Yigit Altay ₁ , Shoupeng Cao ₁ , Hailong Che ₁ , Loai K E A Abdelmohsen ₁ , Jan C M van Hest ₁

Affiliation

Dynamic and adaptive self-assembly systems are able to sense an external or internal (energy or matter) input and respond via chemical or physical property changes. Nanomaterials that show such transient behavior have received increasing interest in the field of nanomedicine due to improved spatiotemporal control of the nanocarrier function. In this regard, much can be learned from the field of systems chemistry and bottom-up synthetic biology, in which complex and intelligent networks of nanomaterials are designed that show transient behavior and function to advance our understanding of the complexity of living systems. In this Perspective, we highlight the recent advancements in adaptive nanomaterials used for nanomedicine and trends in transient responsive self-assembly systems to envisage how these fields can be integrated for the formation of next-generation adaptive stimuli-responsive nanocarriers in nanomedicine.

中文翻译：

适用于仿生和纳米医学的自适应聚合物组件。

动态和自适应的自组装系统能够感应外部或内部（能量或物质）输入，并通过化学或物理性质变化做出响应。由于改进了对纳米载体功能的时空控制，显示出这种瞬时行为的纳米材料在纳米医学领域中受到越来越多的关注。在这方面，可以从系统化学和自下而上的合成生物学领域学到很多东西，其中设计了复杂且智能的纳米材料网络，这些网络显示出瞬时行为和功能，以加深我们对生物系统复杂性的理解。从这个角度来看，

更新日期：2019-11-01

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