Various 2-, 3- and 4-substituted iodobenzenes were aminocarbonylated using aminothiazole and aminothiadiazole derivatives in palladium-catalysed reaction. The reaction is chemospecific toward the corresponding carboxamides. Consequently, the application of the above N-nucleophiles provided the N-1,3-thiazol-2-yl- and N-1,3,4-thiadiazol-2-ylcarboxamides in moderate to high yields. Due to the facile work-up of the reaction mixture isolated yields of 90% or higher were obtained in most cases.

中文翻译：

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氨基噻唑和氨基噻二唑作为碘苯衍生物氨基羰基化中的亲核试剂

使用氨基噻唑和氨基噻二唑衍生物在钯催化的反应中将各种2-，3-和4-取代的碘苯氨基羰基化。该反应对相应的羧酰胺具有化学特异性。因此，上述N-亲核试剂的应用以中等至高产率提供了N -1,3-噻唑-2-基-和N -1,3,4-噻二唑-2-基甲酰胺。由于反应混合物易于后处理，在大多数情况下，分离出的产率为90％或更高。