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Ratio of diastolic to systolic blood pressure represents renal resistive index.
Journal of Human Hypertension ( IF 2.7 ) Pub Date : 2019-10-04 , DOI: 10.1038/s41371-019-0264-1
Tetsuya Akaishi 1 , Michiaki Abe 1, 2 , Takashi Miki 3 , Mika Miki 3 , Yasuharu Funamizu 3 , Sadayoshi Ito 2 , Takaaki Abe 2 , Tadashi Ishii 1
Affiliation  

Increased intrarenal vascular resistance is suggested to accompany chronic kidney diseases (CKD), which is known to be closely associated with hypertension. However, there are few studies that have examined the relationship between blood pressure and intrarenal vascular resistance. Renal color Doppler ultrasonography is one method that can non-invasively evaluate intrarenal vascular resistance. In this study, we comprehensively studied the correlations between ultrasonic parameters and blood pressure indices to elucidate their relationships. In total, 162 patients with suspected CKD were enrolled for this study. Demographics, blood pressure, blood test, urine test, and renal color Doppler ultrasonography data were obtained. The ratio of diastolic to systolic blood pressure (D/S ratio) and pulse pressure were calculated. Our results indicated strong negative correlations between the renal resistive index (RI) values in all four of the studied kidney regions and the D/S ratio. The RI values also showed significant correlations with diastolic pressure and pulse pressure, but they were weaker. Partial correlation coefficients between pulse pressure, mean arterial pressure, D/S ratio, and RI showed that D/S ratio significantly correlated with RI, but pulse pressure or mean arterial pressure did not. Systolic blood pressure did not correlate with any of the studied ultrasonic values. The negative correlation between RI values and the D/S ratio was still observed in subjects without renal dysfunction or any medications. In conclusion, D/S ratio, rather than pulse pressure or mean arterial pressure, would be the most appropriate index to estimate/calculate/judge intrarenal vascular resistance.



中文翻译:


舒张压与收缩压的比值代表肾阻力指数。



肾内血管阻力增加被认为伴随慢性肾脏疾病(CKD),已知慢性肾脏疾病与高血压密切相关。然而,很少有研究探讨血压与肾内血管阻力之间的关系。肾彩色多普勒超声检查是一种可以无创评估肾内血管阻力的方法。在本研究中,我们全面研究了超声参数与血压指标之间的相关性,以阐明它们之间的关系。总共有 162 名疑似 CKD 患者参加了这项研究。获得人口统计学、血压、血液检查、尿液检查和肾脏彩色多普勒超声检查数据。计算舒张压与收缩压的比值(D/S比值)和脉压。我们的结果表明,所有四个研究的肾脏区域的肾抵抗指数 (RI) 值与 D/S 比率之间存在很强的负相关性。 RI值也显示出与舒张压和脉压的显着相关性,但它们的相关性较弱。脉压、平均动脉压、D/S比和RI之间的偏相关系数表明,D/S比与RI显着相关,但脉压或平均动脉压则不显着相关。收缩压与任何研究的超声值均不相关。在没有肾功能障碍或任何药物治疗的受试者中,仍然观察到 RI 值与 D/S 比之间的负相关性。总之,D/S比值,而不是脉压或平均动脉压,将是估计/计算/判断肾内血管阻力的最合适的指标。

更新日期:2019-10-05
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