Endosomes are central stations for converging proteins from biosynthetic pathways and endocytic routes. Many endosomal proteins are sorted to the plasma membrane or the Golgi despite the lysosome being the primary endosomal fate. SNX5 and SNX6 are now revealed to decode a conserved bipartite signal to mediate protein sorting to the Golgi or the plasma membrane.

中文翻译：

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SNX在内体分选中占据中心地位

内体是聚集来自生物合成途径和内吞途径的蛋白质的中心站。尽管溶酶体是主要的内体命运，但许多内体蛋白仍被分选到质膜或高尔基体中。现在显示SNX5和SNX6可以解码保守的二分信号，以介导蛋白质分选到高尔基体或质膜。