The homochirality of biological molecules (right-handed sugars and left-handed amino acids) is a signature of life. Extensive research has been devoted to understanding how enrichment of one enantiomer over the other might have emerged from a prebiotic world. Here, we use experimental data from the model Soai autocatalytic reaction system to evaluate the energy required for symmetry breaking and chiral amplification in molecular self-replication. One postulate for the source of the original imbalance is the tiny difference in energy between enantiomers due to parity violation in the weak force. We discuss the plausibility of parity violation energy difference coupled with asymmetric autocatalysis as a rationalization for absolute asymmetric synthesis and the origin of the homochirality of biological molecules. Our results allow us to identify the magnitude of the energy imbalance that gives rise to directed symmetry breaking and asymmetric amplification in this autocatalytic system.

生物分子（右旋糖和左旋氨基酸）的同质性是生命的标志。广泛的研究致力于了解在益生元世界中如何出现一种对映异构体相对于另一种对映异构体的富集。在这里，我们使用来自模型Soai自催化反应系统的实验数据来评估分子自我复制中对称性破坏和手性扩增所需的能量。造成原始不平衡的原因之一是对映异构体之间的能量差异很小，这是由于弱力中的奇偶性违反所致。我们讨论了奇偶校验违反能量差和不对称自催化的合理性，作为绝对不对称合成的合理化和生物分子同手性的起源。