Shifting electrochemical oxygen reduction towards 2e^– pathway to hydrogen peroxide (H₂O₂), instead of the traditional 4e^– to water, becomes increasingly important as a green method for H₂O₂ generation. Here, through a flexible control of oxygen reduction pathways on different transition metal single atom coordination in carbon nanotube, we discovered Fe-C-O as an efficient H₂O₂ catalyst, with an unprecedented onset of 0.822 V versus reversible hydrogen electrode in 0.1 M KOH to deliver 0.1 mA cm⁻² H₂O₂ current, and a high H₂O₂ selectivity of above 95% in both alkaline and neutral pH. A wide range tuning of 2e^–/4e^– ORR pathways was achieved via different metal centers or neighboring metalloid coordination. Density functional theory calculations indicate that the Fe-C-O motifs, in a sharp contrast to the well-known Fe-C-N for 4e^–, are responsible for the H₂O₂ pathway. This iron single atom catalyst demonstrated an effective water disinfection as a representative application.

将电化学氧还原转向 2e ^（生成过氧化氢 (H ₂ O ₂ )），而不是传统的 4e ^{（生成水），作为 H} ₂ O ₂生成的绿色方法变得越来越重要。在这里，通过灵活控制碳纳米管中不同过渡金属单原子配位的氧还原途径，我们发现Fe-CO作为一种高效的H 2 _O 2_催化剂，与0.1 M KOH中的可逆氢电极相比，具有前所未有的0.822 V起始电压提供0.1 mA cm ^-2 H ₂ O ₂电流，以及在碱性和中性pH值下均高于95%的高H ₂ O _{2选择性。}通过不同的金属中心或邻近的类金属配位实现了2e ^– /4e ^– ORR 途径的大范围调整。密度泛函理论计算表明，与众所周知的 4e ^–的 Fe-CN 基序形成鲜明对比的是，Fe-CO 基序负责 H ₂ O ₂途径。这种铁单原子催化剂作为代表性应用证明了有效的水消毒。