New approach to the synthesis of substituted 7H‐furo[3,2‐b]pyran‐7‐ones based on 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one derivatives,Journal of Heterocyclic Chemistry

当前位置： X-MOL 学术 › J. Heterocycl. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

New approach to the synthesis of substituted 7H‐furo[3,2‐b]pyran‐7‐ones based on 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one derivatives
Journal of Heterocyclic Chemistry ( IF 2.0 ) Pub Date : 2019-09-03 , DOI: 10.1002/jhet.3706
Andrey N. Komogortsev ₁ , Boris V. Lichitsky ₁ , Alexander D. Tretyakov ₁ , Artem N. Fakhrutdinov ₁ , Arkady A. Dudinov ₁ , Michail M. Krayushkin ₁

Affiliation

A convenient approach to the synthesis of the previously unknown 7H‐furo[3,2‐b]pyran‐7‐ones based on the intramolecular cyclization of carbonyl derivatives of 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one has been elaborated. Key intermediates in the synthesis of the target 7H‐furo[3,2‐b]pyran‐7‐ones are 3‐hydroxy‐6‐methyl‐2‐(2‐oxo‐2‐arylethyl)‐4H‐pyran‐4‐ones. They are formed as a result of multicomponent condensation of 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one with arylglyoxals and 4‐methoxyaniline.

中文翻译：

新的方法来取代7的合成ħ -呋喃并[3,2- b ]吡喃-7-酮基于5-羟基-2-甲基-4- ħ -吡喃-4-酮衍生物

一种基于5-羟基-2-甲基-4 H-吡喃-4-基羰基衍生物的分子内环化合成先前未知的7 H-呋喃[3,2 - b ]吡喃-7-酮的简便方法一个已经详细说明。目标7 H-呋喃并[3,2 - b ]吡喃-7-酮的合成的关键中间体是3-羟基-6-甲基-2-（2-氧代-2-芳基乙基）-4 H-吡喃4个。它们是由5-羟基-2-甲基-4-甲基4 H-吡喃-4-酮与芳基乙二醛和4-甲氧基苯胺的多组分缩合形成的。

更新日期：2019-09-03

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南