时间分辨Ter基探针，用于检测锌（II）离子：发光三元络合物形成的研究。,Inorganic Chemistry

当前位置： X-MOL 学术 › Inorg. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

时间分辨Ter基探针，用于检测锌（II）离子：发光三元络合物形成的研究。
Inorganic Chemistry ( IF 4.3 ) Pub Date : 2019-08-27 , DOI: 10.1021/acs.inorgchem.9b01771
Matthew R Winnett ₁ , Parvathy Mini ₁ , Michael R Grace ₁ , Kellie L Tuck ₁

Affiliation

由于其独特的光化学和光物理性质，基于镧系元素的发光络合物长期吸引着化学家。近年来，用于监测生物和环境过程的基于发光镧系元素络合物的探针的报告数量急剧增加，即由于其对特定分析物的选择性，较低的检测限以及它们允许监测分析物的事实实时。基于镧系元素的探针需要与适当的天线/敏化剂配对，以实现最大的能量传输，并且天线通常与稳定的镧系元素螯合物共价连接。我们最近研究了基于“深色”镧系元素的探针，其中敏化剂未与镧系元素螯合物共价连接。在本文中，我们报告了基于“镧” complex络合物，三嗪和Zn2 +之间三元络合物的形成，使用基于镧系元素的发光探针系统检测Zn2 +离子。基于ter（III）的探针包含共价连接到作为Zn2 +离子结合基团的cyclon部分的1,4,7,10-四氮杂环十二烷-1,4,7,10-三乙酸大环螯合剂。在Zn2 +离子和lumazine（一种强烈吸收紫外线的敏化剂）的存在下，会形成1：1：1的三元络合物。所得的络合物具有高发光性，并且对Zn2 +离子具有比对环境有意义的其他阳离子更高的选择性。此外，该探针的检出限为1.2μM，可以检测美国环境保护署（US Environmental Protection Agency）指示的慢性锌（II）浓度水平。

"点击查看英文标题和摘要"

Time-Resolved Terbium-Based Probe for the Detection of Zinc(II) Ions: Investigation of the Formation of a Luminescent Ternary Complex.

Because of their unique photochemical and photophysical properties, luminescent lanthanide-based complexes have long captivated chemists. In recent years, the number of reports of luminescent lanthanide complex-based probes for monitoring of biological and environmental processes has dramatically increased, namely, because of their selectivity for particular analytes, lower limits of detection, and the fact that they allow monitoring of analytes in real time. Lanthanide-based probes need to be paired with an appropriate antenna/sensitizer to allow maximum energy transfer, with the antenna typically covalently attached to the stable lanthanide chelate. We have recently investigated "dark" lanthanide-based probes where the sensitizer is not covalently linked to the lanthanide chelate. Herein we report the use of a luminescent lanthanide-based probe system for the detection of Zn2+ ions based on the formation of a ternary complex between a "dark" terbium complex, lumazine, and Zn2+. The terbium(III)-based probe incorporates a 1,4,7,10-tetraazacyclododecane-1,4,7,10-triacetic acid macrocyclic chelator covalently attached to a cyclen moiety, which is the Zn2+ ion binding group. In the presence of Zn2+ ions and lumazine (a strongly UV-absorbing sensitizer), a 1:1:1 ternary complex forms. The resulting complex is highly luminescent and selective for Zn2+ ions over other cations of environmental significance. Furthermore, with a limit of detection of 1.2 μM, this probe can detect the level of chronic zinc(II) concentrations denoted by the U.S. Environmental Protection Agency.

更新日期：2019-08-27

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南