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The hunt for RNA polymerase II elongation factors: a historical perspective.
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2019-08-22 , DOI: 10.1038/s41594-019-0283-1
Ronald C Conaway 1, 2 , Joan W Conaway 1, 2
Affiliation  

The discovery of the three eukaryotic nuclear RNA polymerases paved the way for serious biochemical investigations of eukaryotic transcription and the identification of eukaryotic transcription factors. Here we describe this adventure from our vantage point, with a focus on the hunt for factors that regulate elongation by RNA polymerase II.

中文翻译:

寻找 RNA 聚合酶 II 延伸因子:历史视角。

三种真核核 RNA 聚合酶的发现为真核转录的生化研究和真核转录因子的鉴定铺平了道路。在这里,我们从我们的有利位置描述了这次冒险,重点是寻找调节 RNA 聚合酶 II 延伸的因素。
更新日期:2019-08-23
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