A β-cyclodextrin-functionalized magnetic zinc-metal organic framework (M-MOF/β-CD) was synthesized via a facile one-pot reaction. M-MOF/β-CD was used as a magnetic porous absorbent for the extraction and determination of prochloraz and three triazole fungicides in vegetable samples. M-MOF/β-CD was prepared by creating MOF layers on the surface of a Fe₃O₄–graphene oxide (GO) nanocomposite and bonding them with β-CD molecules. Characterization suggested that a 3D porous structure was formed, with M-MOF/β-CD exhibiting high superparamagnetism and a large surface area. As a new strategy, integrating MOFs with Fe₃O₄–GO could improve their water-resistance and mechanical strength by providing a rigid nanosupport interface. Combining M-MOF and β-CD resulted in excellent selective adsorption capacities for prochloraz and three triazole fungicides. The static adsorption process was evaluated and the results were in good agreement with the Freundlich model. Subsequently, M-MOF/β-CD was applied to extracting prochloraz and triazole fungicides from tomato and lettuce vegetables, followed by HPLC-MS/MS determination. The limits of detection for the above fungicides were found to be 0.25–1.0 μg/L at a signal-to-noise ratio of 3, with spiked recoveries of 74.13%–119.83%, indicating that M-MOF/β-CD was promising for application to the extraction and determination of fungicides in complex matrices.

通过简单的一锅反应合成了β-环糊精官能化的磁性锌金属有机骨架（M-MOF /β-CD）。M-MOF /β-CD用作磁性多孔吸收剂，用于萃取和测定蔬菜样品中的百草枯和三种三唑类杀菌剂。M-MOF /β-CD的制备方法是在Fe ₃ O _4-氧化石墨烯（GO）纳米复合材料的表面上形成MOF层，然后将其与β-CD分子键合。表征表明形成了3D多孔结构，其中M-MOF /β-CD表现出高的超顺磁性和大的表面积。作为新策略，将MOF与Fe ₃ O ₄集成–GO可以通过提供刚性的纳米载体界面来提高其防水性和机械强度。M-MOF和β-CD的结合产生了对丙草胺和三种三唑类杀真菌剂极好的选择性吸附能力。对静态吸附过程进行了评估，结果与Freundlich模型非常吻合。随后，将M-MOF /β-CD应用于从番茄和生菜蔬菜中提取前杀菌剂和三唑类杀菌剂，然后进行HPLC-MS / MS测定。发现上述杀菌剂的检出限为0.25–1.0μg/ L，信噪比为3，加标回收率为74.13％–119.83％，表明M-MOF /β-CD很有前景用于复杂基质中杀菌剂的提取和测定。