The surface of poly(methyl methacrylate) nanospheres (PMMA-NSs) was molecularly imprinted with sulfadiazine by a surface imprinting method. Simultaneously, Mn(II)-doped ZnS quantum dots were incorporated into the imprinted PMMA-NSs. The morphology of the fluorescent nanoprobe was characterized by transmission electron microscopy which revealed good spheroidal core-shell structure and a homogeneous distribution of the QDs. Following binding of sulfadiazine, fluorescence (best measured at excitation/emission maxima of 335/592 nm) is increasingly quenched. The detection range is 5–40 μmol·L−1 of sulfadiazine, and the detection limit is 0.24 μmol·L−1. The fluorescence quenching mechanism is discussed, and a photo-induced electron transfer process is shown to account for quenching. The fluorescent probe was applied to the determination of sulfadiazine in spiked tap water with recoveries and RSDs of 96.6–100.2% and 2.7–3.9%, respectively. The detection of sulfadiazine in spiked lake water exhibited the recoveries and RSDs with 99.3–104.8% and 1.8–4.2%, respectively. Graphical abstract Schematic presentation of synthesis of PMMA-Ns, Mn-doped ZnS QDs, MQPs, and the elution diagram of SD from MQPs, and the relative reagents including: sodium dodecyl benzene sulfonate(SDBS), (3-aminopropyl)triethoxysilane(APTES), 3-mercaptopropionic acid (MPA), tetraethylorthosilicate(TEOS)and sulfadiazine(SD), and nanoparticles including: polymer(methyl methacrylate) nanospheres(PMMANs), MIPs@QDs@PMMANs(MQPs) and carbon quantum dots(CQDs). Schematic presentation of synthesis of PMMA-Ns, Mn-doped ZnS QDs, MQPs, and the elution diagram of SD from MQPs, and the relative reagents including: sodium dodecyl benzene sulfonate(SDBS), (3-aminopropyl)triethoxysilane(APTES), 3-mercaptopropionic acid (MPA), tetraethylorthosilicate(TEOS)and sulfadiazine(SD), and nanoparticles including: polymer(methyl methacrylate) nanospheres(PMMANs), MIPs@QDs@PMMANs(MQPs) and carbon quantum dots(CQDs).

中文翻译：

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使用掺杂锰 (II) 掺杂 ZnS 量子点的分子印迹聚甲基丙烯酸甲酯纳米珠荧光测定磺胺嘧啶

聚（甲基丙烯酸甲酯）纳米球（PMMA-NSs）的表面通过表面印迹方法用磺胺嘧啶进行分子印迹。同时，将 Mn(II) 掺杂的 ZnS 量子点结合到印迹的 PMMA-NS 中。荧光纳米探针的形态通过透射电子显微镜进行表征，其显示出良好的球形核壳结构和均匀分布的 QD。磺胺嘧啶结合后，荧光（最好在 335/592 nm 的激发/发射最大值处测量）逐渐淬灭。磺胺嘧啶的检测范围为5-40 μmol·L-1，检出限为0.24 μmol·L-1。讨论了荧光猝灭机制，并显示了光诱导电子转移过程来解释猝灭。荧光探针用于测定加标自来水中的磺胺嘧啶，回收率和 RSD 分别为 96.6-100.2% 和 2.7-3.9%。加标湖水中磺胺嘧啶的检测显示回收率和 RSD 分别为 99.3-104.8% 和 1.8-4.2%。图形摘要 PMMA-Ns、Mn 掺杂的 ZnS QDs、MQPs 的合成示意图，以及 SD 从 MQPs 的洗脱图，相关试剂包括：十二烷基苯磺酸钠 (SDBS)、(3-氨基丙基)三乙氧基硅烷 (APTES) )、3-巯基丙酸 (MPA)、原硅酸四乙酯 (TEOS) 和磺胺嘧啶 (SD)，以及纳米颗粒，包括：聚合物（甲基丙烯酸甲酯）纳米球（PMMANs）、MIPs@QDs@PMMANs（MQPs）和碳量子点（CQDs）。PMMA-Ns、Mn掺杂的ZnS QDs、MQPs的合成示意图，